Structure of PDB 1zm9 Chain F

Receptor sequence
>1zm9F (length=207) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
EFLGDGGDVSFSTRGTQNWTVERLLQAHRQLEERGYVFVGYHGTFLEAAQ
SIVFGGVRARSQDLDAIWRGFYIAGDPALAYGYAQDQEPDARGRIRNGAL
LRVYVPRSSLPGFYRTSLTLAAPEAAGEVERLIGHPLPLRLDAITGPEEE
GGRLETILGWPLAERTVVIPSAIPTDPRNVGGDLDPSSIPDKEQAISALP
DYASQPG
3D structure
PDB1zm9 Exotoxin A-eEF2 complex structure indicates ADP ribosylation by ribosome mimicry.
ChainF
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E553
Catalytic site (residue number reindexed from 1) E155
Enzyme Commision number 2.4.2.36: NAD(+)--diphthamide ADP-ribosyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 P34 F H440 G441 Y470 I471 A478 Y481 H42 G43 Y72 I73 A80 Y83
Gene Ontology
Molecular Function
GO:0047286 NAD+-diphthamide ADP-ribosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1zm9, PDBe:1zm9, PDBj:1zm9
PDBsum1zm9
PubMed16107839
UniProtP11439|TOXA_PSEAE Exotoxin A (Gene Name=eta)

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