Structure of PDB 1xcb Chain F

Receptor sequence
>1xcbF (length=200) Species: 271 (Thermus aquaticus) [Search protein sequence]
VPEAAISRLITYLRILEELEAQGVHRTSSEQLGELAQVTAFQVRKDLSYF
GSYGYTVPVLKRELRHILGLNRKWGLCIVGMGRLGSALADYPGFGESFEL
RGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPREAAQKAA
DLLVAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAILNPKWRE
3D structure
PDB1xcb X-Ray Structure of a Rex-Family Repressor/NADH Complex: Insights into the Mechanism of Redox Sensing
ChainF
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD F A94 Y98 A87 Y91
BS02 NAD F G89 R90 L91 D112 V113 D114 K117 T147 V148 P149 F171 P173 D188 F189 G82 R83 L84 D105 V106 D107 K110 T140 V141 P142 F164 P166 D181 F182
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0042802 identical protein binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
GO:0051775 response to redox state
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:1xcb, PDBe:1xcb, PDBj:1xcb
PDBsum1xcb
PubMed15642260
UniProtQ9X2V5|REX_THEAQ Redox-sensing transcriptional repressor Rex (Gene Name=rex)

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