Structure of PDB 1u10 Chain F

Receptor sequence
>1u10F (length=240) Species: 562 (Escherichia coli) [Search protein sequence]
ATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYF
GHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDV
DIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEIFSLIKLAAQ
DKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPAD
SLECEDQPLPPSGDGCGAELQSWFEPLPPSCQALLDEHVI
3D structure
PDB1u10 Peptidoglycan amidase MepA is a LAS metallopeptidase
ChainF
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN F D147 H150 D128 H131
BS02 ZN F H110 H113 D120 H211 H91 H94 D101 H192
Gene Ontology
Molecular Function
GO:0004175 endopeptidase activity
GO:0004222 metalloendopeptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0000270 peptidoglycan metabolic process
GO:0006508 proteolysis
GO:0009252 peptidoglycan biosynthetic process
GO:0009410 response to xenobiotic stimulus
Cellular Component
GO:0030288 outer membrane-bounded periplasmic space
GO:0042597 periplasmic space

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Cellular Component
External links
PDB RCSB:1u10, PDBe:1u10, PDBj:1u10
PDBsum1u10
PubMed15292190
UniProtP0C0T5|MEPA_ECOLI Penicillin-insensitive murein endopeptidase (Gene Name=mepA)

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