Structure of PDB 1tye Chain F

Receptor sequence
>1tyeF (length=440) Species: 9606 (Homo sapiens) [Search protein sequence]
GPNICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCA
PESIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNF
SIQVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLR
IGFGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQV
TRFNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTT
DAKTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLS
QKNINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGK
IRSKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIE
AKVRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQ
3D structure
PDB1tye Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
ChainF
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MG F S121 S123 E220 S121 S123 E220
BS02 CA F S123 D126 D127 D251 S123 D126 D127 D251
BS03 CA F D158 N215 D217 A218 P219 E220 D158 N215 D217 A218 P219 E220
External links
PDB RCSB:1tye, PDBe:1tye, PDBj:1tye
PDBsum1tye
PubMed15378069
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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