Structure of PDB 1svm Chain F

Receptor sequence
>1svmF (length=363) [Search protein sequence]
TKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHY
KYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNR
FNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVY
NIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVA
IDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHL
NKRTQIFPPGIVTMNEYSVPKTLQARFVKQIDFRPKDYLKHCLERSEFLL
EKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQK
MKFNVAMGIGVLD
3D structure
PDB1svm Mechanisms of conformational change for a replicative hexameric helicase of SV40 large tumor antigen.
ChainF
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP F K418 R540 K154 R276
BS02 ZN F C302 C305 H313 H317 C38 C41 H49 H53
BS03 ATP F I428 D429 S430 G431 K432 T433 T434 P549 K550 L553 L557 I164 D165 S166 G167 K168 T169 T170 P285 K286 L289 L293
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
Biological Process
GO:0006260 DNA replication

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1svm, PDBe:1svm, PDBj:1svm
PDBsum1svm
PubMed15454080
UniProtP03070|LT_SV40 Large T antigen

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