Structure of PDB 1qiy Chain F
Receptor sequence
>1qiyF (length=30) Species:
9606
(Homo sapiens) [
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FVNQYLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
1qiy
Structural Consequences of the B5 Histidine --> Tyrosine Mutation in Human Insulin Characterized by X-Ray Crystallography and Conformational Analysis.
Chain
F
Resolution
2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
F
F1 V2
F1 V2
BS02
peptide
F
C7 L11 V18 C19 R22 G23 F24 F25
C7 L11 V18 C19 R22 G23 F24 F25
BS03
IPH
F
L11 A14
L11 A14
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:1qiy
,
PDBe:1qiy
,
PDBj:1qiy
PDBsum
1qiy
PubMed
10508408
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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