Structure of PDB 1n86 Chain F

Receptor sequence
>1n86F (length=295) Species: 9606 (Homo sapiens) [Search protein sequence]
EASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIH
DITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQK
RLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYAL
RVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFG
DDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNG
VYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNR
3D structure
PDB1n86 The crystal structure of fragment double-D from cross-linked lamprey fibrin reveals isopeptide linkages across an unexpected D-D interface.
ChainF
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F F295 D301 T305 F322 Q329 K338 C339 H340 Y363 D364 F199 D205 T209 F226 Q233 K242 C243 H244 Y267 D268
BS02 CA F D318 D320 F322 E323 G324 D222 D224 F226 E227 G228
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1n86, PDBe:1n86, PDBj:1n86
PDBsum1n86
PubMed12501189
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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