Structure of PDB 1m19 Chain F

Receptor sequence
>1m19F (length=86) Species: 8355 (Xenopus laevis) [Search protein sequence]
RHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVI
RDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB1m19 Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
ChainF
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F R235 R245 I246 S247 G248 R278 K279 T280 R19 R29 I30 S31 G32 R62 K63 T64 PDBbind-CN: Kd=0.6uM
BS02 dna F R219 P232 R236 R245 R3 P16 R20 R29 PDBbind-CN: Kd=0.6uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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External links
PDB RCSB:1m19, PDBe:1m19, PDBj:1m19
PDBsum1m19
PubMed12559907
UniProtP62799|H4_XENLA Histone H4

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