Structure of PDB 1m18 Chain F

Receptor sequence
>1m18F (length=83) Species: 8355 (Xenopus laevis) [Search protein sequence]
KVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDA
VTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG
3D structure
PDB1m18 Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
ChainF
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna F R235 R245 I246 S247 G248 R278 K279 T280 R16 R26 I27 S28 G29 R59 K60 T61 PDBbind-CN: Kd=0.6uM
BS02 dna F T230 P232 R236 R245 T11 P13 R17 R26 PDBbind-CN: Kd=0.6uM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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External links
PDB RCSB:1m18, PDBe:1m18, PDBj:1m18
PDBsum1m18
PubMed12559907
UniProtP62799|H4_XENLA Histone H4

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