Structure of PDB 1ltj Chain F

Receptor sequence
>1ltjF (length=285) Species: 9606 (Homo sapiens) [Search protein sequence]
LQEIYNSNNQKIVNLKEKVAQLEAQCQEPCKDTVQIHDITGKDCQDIANK
GAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFKKNWI
QYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTST
ADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNG
MQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYYQGGTYSKAST
PNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRLTI
3D structure
PDB1ltj 2.8 A Crystal Structures of Recombinant Fibrinogen Fragment D with and without Two Peptide Ligands: GHRP Binding to the "b" Site Disrupts Its Nearby Calcium-binding Site.
ChainF
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F F295 D301 F322 Q329 K338 C339 H340 Y363 D364 F186 D192 F213 Q220 K229 C230 H231 Y254 D255
BS02 CA F D318 D320 F322 G324 D209 D211 F213 G215
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ltj, PDBe:1ltj, PDBj:1ltj
PDBsum1ltj
PubMed12356313
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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