Structure of PDB 1ibw Chain F

Receptor sequence
>1ibwF (length=228) Species: 1593 (Lactobacillus sp. 30A) [Search protein sequence]
FTGVQGRVIGYDILRSPEVDKAKPLFTETQWDGSELPIYDAKPLQDALVE
YFGTEQDRRHYPAPGSFIVCANKGVTAERPKNDADMKPGQGYGVWSAIAI
SFAKDPTKDSSMFVEDAGVWETPNEDELLEYLEGRRKAMAKSIAECGQDA
HASFESSWIGFAYTMMEPGQIGNAITVAPYVSLPIDSIPGGSILTPDKDM
EIMENLTMPEWLEKMGYKSLSANNALKY
3D structure
PDB1ibw Structure and cooperativity of a T-state mutant of histidine decarboxylase from Lactobacillus 30a.
ChainF
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) F195 E197
Catalytic site (residue number reindexed from 1) F113 E115
Enzyme Commision number 4.1.1.22: histidine decarboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PYR F F83 M194 F195 F1 M112 F113
BS02 PVH F F83 A153 F195 V196 E197 F1 A71 F113 V114 E115
Gene Ontology
Molecular Function
GO:0004398 histidine decarboxylase activity
GO:0016831 carboxy-lyase activity
Biological Process
GO:0006520 amino acid metabolic process
GO:0006547 L-histidine metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1ibw, PDBe:1ibw, PDBj:1ibw
PDBsum1ibw
PubMed11835507
UniProtP00862|DCHS_LACS3 Histidine decarboxylase proenzyme (Gene Name=hdcA)

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