Structure of PDB 1gmo Chain F

Receptor sequence
>1gmoF (length=173) Species: 9606 (Homo sapiens) [Search protein sequence]
NTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCADRCTRNKGLPFTCKA
FVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSY
KGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG
PWCFTSNPEVRYEVCDIPQCSEV
3D structure
PDB1gmo Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor
ChainF
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SGN F R134 Y167 R181 R98 Y131 R145
BS02 SGN F T61 K62 K63 T25 K26 K27
BS03 SGN F R73 G79 R37 G43
BS04 SO4 F R126 I129 I130 S135 R90 I93 I94 S99
BS05 SO4 F R168 G169 D171 R132 G133 D135
External links
PDB RCSB:1gmo, PDBe:1gmo, PDBj:1gmo
PDBsum1gmo
PubMed11597998
UniProtP14210|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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