Structure of PDB 1gmd Chain F

Receptor sequence

>1gmdF (length=131) Species: 9913 (Bos taurus) [Search protein sequence]

IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY

3D structure

PDB

1gmd X-ray crystal structure of gamma-chymotrypsin in hexane.

Chain

Resolution

2.2 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	H57 D102
Catalytic site (residue number reindexed from 1)	H42 D87
Enzyme Commision number	3.4.21.1: chymotrypsin.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	peptide	F	I16 V23 S26 W27 Q116 A120 C122	I1 V8 S11 W12 Q101 A105 C107
BS02	peptide	F	F41 C42 H57	F26 C27 H42
BS03	HEX	F	I16 N18 G19 T144	I1 N3 G4 T129
BS04	HEX	F	W27 W29 V137 T138 T139	W12 W14 V122 T123 T124
BS05	HEX	F	L143 Y146	L128 Y131
BS06	HEX	F	P28 Q30 V31 S32 V67 A68 G69 E70 W141	P13 Q15 V16 S17 V52 A53 G54 E55 W126
BS07	HEX	F	H57 Y94 S96	H42 Y79 S81

Gene Ontology

	Molecular Function
GO:0004252	serine-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

External links

PDB	RCSB:1gmd, PDBe:1gmd, PDBj:1gmd
PDBsum	1gmd
PubMed	8003497
UniProt	P00766\|CTRA_BOVIN Chymotrypsinogen A