Structure of PDB 1gle Chain F

Receptor sequence

>1gleF (length=161) Species: 562 (Escherichia coli)

GLFDKLKSLVSTIEIIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGN
KMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGEGFKRIA
EEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVT
VGETPVIRIKK

3D structure

• PDB: 1gle Cation-promoted association of a regulatory and target protein is controlled by protein phosphorylation.
• Chain: F
• Resolution: 2.94 Å

Enzymatic activity

• Enzyme Commision number: 2.7.1.69: Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	F	H75 H90	H68 H83

Gene Ontology

Molecular Function

• GO:0005515 protein binding
• GO:0016301 kinase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0009401 phosphoenolpyruvate-dependent sugar phosphotransferase system
• GO:0016310 phosphorylation
• GO:0034763 negative regulation of transmembrane transport
• GO:0043610 regulation of carbohydrate utilization
• GO:0045912 negative regulation of carbohydrate metabolic process
• GO:1902344 negative regulation of maltose transport

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0009898 cytoplasmic side of plasma membrane
• GO:0016020 membrane
• GO:1902495 transmembrane transporter complex
• GO:1990154 enzyme IIA-maltose transporter complex

External links

• PDB: RCSB:1gle, PDBe:1gle, PDBj:1gle
• PDBsum: 1gle
• PubMed: 8170944
• UniProt: P69783|PTGA_ECOLI PTS system glucose-specific EIIA component (Gene Name=crr)