Structure of PDB 1fzb Chain F

Receptor sequence
>1fzbF (length=311) Species: 9606 (Homo sapiens) [Search protein sequence]
KMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE
PCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGS
GNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLIS
TQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAG
DAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMN
KCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKII
PFNRLTIGEGQ
3D structure
PDB1fzb Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
ChainF
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide F F322 Q329 D330 K338 C339 H340 Y363 D364 F235 Q242 D243 K251 C252 H253 Y276 D277
BS02 CA F D318 D320 F322 E323 G324 N325 D231 D233 F235 E236 G237 N238
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1fzb, PDBe:1fzb, PDBj:1fzb
PDBsum1fzb
PubMed9333233
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

[Back to BioLiP]