Structure of PDB 1ev6 Chain F
Receptor sequence
>1ev6F (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
1ev6
R6 Hexameric Insulin Complexed with m-Cresol or Resorcinol
Chain
F
Resolution
1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
F
F1 V2
F1 V2
BS02
peptide
F
L6 S9 H10
L6 S9 H10
BS03
peptide
F
C7 L11 V18 C19 R22 G23 F24 Y26 T30
C7 L11 V18 C19 R22 G23 F24 Y26 T30
BS04
peptide
F
H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26 P28
H5 G8 S9 V12 E13 Y16 G23 F24 F25 Y26 P28
BS05
peptide
F
N3 H10
N3 H10
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:1ev6
,
PDBe:1ev6
,
PDBj:1ev6
PDBsum
1ev6
PubMed
11092919
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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