Structure of PDB 8otz Chain EK

Receptor sequence
>8otzEK (length=437) Species: 9913 (Bos taurus) [Search protein sequence]
MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGDDSFNTF
FSETGAGKHVPRAVFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANN
YARGHYTIGKEIVDLVLDRIRKLADLCTGLQGFLIFHSFGGGTGSGFASL
LMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAF
MVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDL
TEFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQM
VKCDPRHGKYMACCMLYRGDVVPKDVNAAIATIKTKRTIQFVDWCPTGFK
VGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWARLDHKLDLMYAKR
AFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGVDS
3D structure
PDB8otz Structural specializations of the sperm tail.
ChainEK
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GTP EK Q11 A12 S140 G142 G143 T145 I171 T179 N206 Y224 N228 Q11 A12 S138 G140 G141 T143 I169 T177 N204 Y222 N226
Gene Ontology
Molecular Function
GO:0005200 structural constituent of cytoskeleton
GO:0005525 GTP binding
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007017 microtubule-based process
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8otz, PDBe:8otz, PDBj:8otz
PDBsum8otz
PubMed37327785
UniProtQ32KN8|TBA3_BOVIN Tubulin alpha-3 chain (Gene Name=TUBA3)

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