Structure of PDB 6yxx Chain EG

Receptor sequence

>6yxxEG (length=154) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence]

NIKGGVGSFLMRRAAPKSIRQKYQTGPQFYKRKFFQFQKGHHRLHRRISG
VQTGSPTHQREYERFHHLPGDVRTRPQFDFTFGETRADRVMFAWRKRGDL
QLYQMSGRGETFVCYRCGYPVRSQLVAVKADNWDYRMCYRCYTNTVHRGM
ENDT

3D structure

PDB

6yxx Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.

Chain

Resolution

3.9 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	EG	N3 K5 S10 R14 R15 K19 S20 R22 Q23 Y25 Q26 G28 Q30 F31 Y32 K33 R34 K35 F36 Q38 K41 G42 H43 H44 R45 R48 R49 S51 G52 Q54 E65 R66 H68 R77 G109 R110 R118 Y121 Q126 N146 R150	N1 K3 S8 R12 R13 K17 S18 R20 Q21 Y23 Q24 G26 Q28 F29 Y30 K31 R32 K33 F34 Q36 K39 G40 H41 H42 R43 R46 R47 S49 G50 Q52 E63 R64 H66 R75 G107 R108 R116 Y119 Q124 N144 R148
BS02	ZN	EG	C116 C119 C143	C114 C117 C141

Gene Ontology

	Cellular Component
GO:0005730	nucleolus

View graph for
Cellular Component

External links

PDB	RCSB:6yxx, PDBe:6yxx, PDBj:6yxx
PDBsum	6yxx
PubMed	32679035
UniProt	Q387S8

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