Structure of PDB 7b6a Chain EEE

Receptor sequence
>7b6aEEE (length=266) Species: 1891762 (Betapolyomavirus hominis) [Search protein sequence]
VEVLEVKTGVDAITEVECFLNPEMGDPDENLRGFSLKLSAENDFSSDSPE
RKMLPCYSTARIPLPNLNEDLTCGNLLMWEAVTVQTEVIGITSMLNLHAG
SQKVHEHGGGKPIQGSNFHFFAVGGEPLEMQGVLMNYRSKYPDGTITPKN
PTAQSQVMNTDHKAYLDKNNAYPVECWVPDPSRNENARYFGTFTGGENVP
PVLHVTNTATTVLLDEQGVGPLCKADSLYVSAADICGLFTNSSGTQQWRG
LARYFKIRLRKRSVKN
3D structure
PDB7b6a Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors.
ChainEEE
Resolution1.44 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA EEE E48 K287 E17 K256
BS02 CA EEE S213 E216 S182 E185
BS03 CA EEE G156 E157 K255 S258 Y260 G125 E126 K224 S227 Y229
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity
Cellular Component
GO:0019028 viral capsid

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Molecular Function
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Cellular Component
External links
PDB RCSB:7b6a, PDBe:7b6a, PDBj:7b6a
PDBsum7b6a
PubMed35974998
UniProtP03088|VP1_POVBK Major capsid protein VP1

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