Structure of PDB 5i4l Chain E0

Receptor sequence
>5i4lE0 (length=60) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
AKVHGSLARAGKVKSQTPKVEKTEKPKKPKGRAYKRLLYTRRFVNVTLVN
GKRRMNPGPS
3D structure
PDB5i4l Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
ChainE0
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna E0 A2 R10 G12 K13 V14 K15 Q17 T18 P19 T24 K26 K28 P30 K31 G32 R33 R37 R43 N46 R55 M56 N57 A1 R9 G11 K12 V13 K14 Q16 T17 P18 T23 K25 K27 P29 K30 G31 R32 R36 R42 N45 R54 M55 N56
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0010494 cytoplasmic stress granule
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:5i4l, PDBe:5i4l, PDBj:5i4l
PDBsum5i4l
PubMed27296282
UniProtP0CX33|RS30A_YEAST Small ribosomal subunit protein eS30A (Gene Name=RPS30A)

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