Structure of PDB 9f9a Chain E

Receptor sequence
>9f9aE (length=187) Species: 9606 (Homo sapiens) [Search protein sequence]
PLELRPGEYRVLLCVDIGETRGGGHRPELLRELQRLHVTHTVRKLHVGDF
VWVAQETNPRDPANPGELVLDHIVERKRLDDLCSSIIDGRFREQKFRLKR
CGLERRVYLVEELSLPESTLLQAVTNTQVIDGFFVKRTADIKESAAYLAL
LTRGLQRLYQGHTLRSRPWGTPPNPLCSLLTFSDFNA
3D structure
PDB9f9a Fragment-Based Discovery of Novel MUS81 Inhibitors.
ChainE
Resolution2.911 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A1IA6 E E351 F354 R355 R358 E93 F96 R97 R100
BS02 A1IA6 E D307 E333 K335 S342 Q352 D49 E75 K77 S84 Q94
BS03 MG E D274 D307 D16 D49
BS04 MG E D307 E333 R334 D49 E75 R76
External links
PDB RCSB:9f9a, PDBe:9f9a, PDBj:9f9a
PDBsum9f9a
PubMed39015284
UniProtQ96NY9|MUS81_HUMAN Crossover junction endonuclease MUS81 (Gene Name=MUS81)

[Back to BioLiP]