Structure of PDB 9c4m Chain E

Receptor sequence
>9c4mE (length=335) Species: 470 (Acinetobacter baumannii) [Search protein sequence]
MLTIVQEALTFDDVLLLPAYSTVLPKDVSLKTRLTRGIYLNIPLVSAAMD
TVTESRMAIAMAQNGGIGILHKNMDIAAQAAEVRRVKKFEAGYPNSCKDD
LGRLRVGAAVGTGADTPSRVEALVEAGVDVIVVDTAHGHSAGVIERVRWV
KQNFPQVQVIGGNIATGDAALALLDAGADAVKVGIGPGSICTTRIVAGIG
MPQISAIDSVASALKDQIPLIADGGIRFSGDMAKAIGAGASTIMVGSLLA
GTEEAPGEVEFFQGRYYKAYRGMGSLGAMALVPEGIEGRVPYKGPMGNIV
HQMMGGLRSSMGYTGSAVIEDLRQNAKFVKITSAG
3D structure
PDB9c4m Differential effects of inosine monophosphate dehydrogenase (IMPDH/GuaB) inhibition in Acinetobacter baumannii and Escherichia coli.
ChainE
Resolution2.48 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IMP E M49 G301 S302 I303 C304 D336 G338 G359 S360 Y383 G385 M386 G387 E416 M49 G188 S189 I190 C191 D223 G225 G246 S247 Y270 G272 M273 G274 E284
BS02 A1AUF E A249 H250 G387 E416 A136 H137 G274 E284
BS03 A1AUF E P25 G444 Y445 P25 G312 Y313
External links
PDB RCSB:9c4m, PDBe:9c4m, PDBj:9c4m
PDBsum9c4m
PubMed39235234
UniProtP31002|IMDH_ACICA Inosine-5'-monophosphate dehydrogenase (Gene Name=guaB)

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