Structure of PDB 8ybk Chain E

Receptor sequence
>8ybkE (length=79) Species: 9606 (Homo sapiens) [Search protein sequence]
STELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACKAYLVGLFED
TNLCAIHAKRVTIMPKDIQLARRIRGERA
3D structure
PDB8ybk Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
ChainE
Resolution2.69 Å
3D
structure
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Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E R63 L65 R69 R7 L9 R13
BS02 dna E R72 R83 V117 T118 R16 R27 V61 T62
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0045296 cadherin binding
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:8ybk, PDBe:8ybk, PDBj:8ybk
PDBsum8ybk
PubMed38972377
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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