Structure of PDB 8xj7 Chain E

Receptor sequence
>8xj7E (length=364) Species: 10244 (Monkeypox virus) [Search protein sequence]
NKLFNIAQRILDTNSVLLTERGDHIVWINNSWKFNSEEPLITKLILSIRH
QLPKEYSSELLCPRKRKTVEANIRDMLVDSVETDTYPDKLPFKNGVLDLV
DGMFYSGDDAKKYTCTVSTGFKFDDTKFVEDSPEMEELMNIINDIQPLTD
ENKKNRELYEKTLSSCLCGATKGCLTFFFGETATGKSTTKRLLKSAIGDL
FVETGQTILTDPFIANMHLKRSVFCSELPDFACKKIRSDNIKKLTEPCVI
NRNHATIIIDTNYKPVFDRIDNALMRRIAVVRFRTHFSQPSGREAAENND
AYDKVKLLDEGLDGKIQNNRYRFAFLYLLVKWYKKYHIPIMKLYPTPEEI
PDFAFYLKIGTLLV
3D structure
PDB8xj7 Structural and functional insights into the helicase protein E5 of Mpox virus.
ChainE
Resolution2.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ANP E R619 R620 R276 R277
BS02 ANP E I464 A506 T507 G508 K509 S510 T511 F630 D652 L655 I141 A183 T184 G185 K186 S187 T188 F287 D309 L312
Gene Ontology
Molecular Function
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Cellular Component
GO:0030430 host cell cytoplasm

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8xj7, PDBe:8xj7, PDBj:8xj7
PDBsum8xj7
PubMed38914567
UniProtA0A7H0DN89|PG117_MONPV Uncoating factor OPG117 (Gene Name=OPG117)

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