Structure of PDB 8x1c Chain E

Receptor sequence
>8x1cE (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
AKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEIL
ELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQA
VLLPK
3D structure
PDB8x1c Structure of nucleosome-bound SRCAP-C in the ADP-bound state
ChainE
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna E R42 V43 G44 A45 T76 R77 R29 V30 G31 A32 T63 R64
BS02 dna E A14 K15 R17 G28 R32 R42 R77 A1 K2 R4 G15 R19 R29 R64
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0031492 nucleosomal DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0008285 negative regulation of cell population proliferation
GO:0031507 heterochromatin formation
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Cellular Component
External links
PDB RCSB:8x1c, PDBe:8x1c, PDBj:8x1c
PDBsum8x1c
PubMed38331872
UniProtQ93077|H2A1C_HUMAN Histone H2A type 1-C (Gene Name=H2AC6)

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