Structure of PDB 8wlo Chain E

Receptor sequence

>8wloE (length=597) Species: 9833 (Hippopotamus amphibius)

QSTTEEQAKTFLLKFDHDAEDLSYQSSLASWNYNTNITDENVQKMNEARA
KWSAFYEEQSKAAKMFSLEEIQDLTLKRQLQALQQSGTSALSADKSKRLN
TILNTMSTIYSSGKVLDPNTQECLVLEPGLDDIMENSQDYSRRLWAWEGW
RAEVGKQLRPLYEEYVVLENEMARANNYEDYGDYWRGDYEVTGAGDYDYS
RDQLITDVERTFAEIKPLYEQLHAYVRTKLMDAYPSHISPTGCLPAHLLG
DMWGRFWTNLYPLTVPFGQKPSIDVTREMENQSWDTKRIFKEAEKFFVSI
GLPNMTQGFWDNSMLTEPGDGRKVVCHPTAWDLGKGDFRIKMCTKVTMDD
FLTAHHEMGHIQYDMAYATQPYLLRNGANEGFHEAVGEIMSLSAATPHYL
KALGLLPPDFYEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGKI
PKEQWMQKWWEMKREIVGVVEPLPHDETYCDPACLFHVAEDYSFIRYYTR
TIYQFQFHEALCQTAKHEGPLYKCDISNSTDAGQRLLQMLNLGKSEPWTL
ALERIVGAKTMDVKPLLNYFEPLLTWLKDQNGNSFVGWSTDWTPYSE

3D structure

• PDB: 8wlo Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2
• Chain: E
• Resolution: 2.62 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	E	H374 H378	H356 H360

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Mon Nov 25 20:03:36 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '8wlo', asym_id = 'E', title = 'Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2'

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='8wlo', asym_id='E', title='Molecular basis of hippopotamus ACE2 binding to SARS-CoV-2')

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0006508,0008237,0008241,0016020', uniprot = '', pdbid = '8wlo', asym_id = 'E'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0006508,0008237,0008241,0016020', uniprot='', pdbid='8wlo', asym_id='E')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>