Structure of PDB 8w9c Chain E

Receptor sequence
>8w9cE (length=353) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
DSKVSVTGLPLNKGPSEKIKRESLWNDLKTFLTENMTEESNIRSTIGWNG
IDFENEDFCSACNQSGSFLCCDTCPKSFHFLCLDPPIDPNNLPKGDWHCN
ECKFKIFINNSMATLKKIESNFIKQNNNVKIFAKLLFNIDSHNPKQFQLP
NYIKETFPAVKTGSRGQYSDENDKIPLTDRQLFNTSYGQSITKLDSYNPD
THIDSNSGKFLICYKCNQTRLGSWSHPENSRLIMTCDYCQTPWHLDCVPR
ASFKNLGSKWKCPLHSPTKVYKKIYKVWKKQRLINKKNQLYYEPLQKIGY
QNNGNIQIIPKITQIDENSIKYDFFDKIYKSKMVQKRKLFQFQESLIDKL
VSN
3D structure
PDB8w9c Structures and dynamics of Rpd3S complex bound to nucleosome.
ChainE
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN E C263 H283 C286 C59 H79 C82
BS02 ZN E C275 C303 C306 C71 C99 C102
BS03 ZN E C440 C466 C236 C262
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8w9c, PDBe:8w9c, PDBj:8w9c
PDBsum8w9c
PubMed38598631
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

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