Structure of PDB 8w7e Chain E

Receptor sequence
>8w7eE (length=174) Species: 9606 (Homo sapiens) [Search protein sequence]
LIPIVVRAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFLQSESNKKP
IHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGSLLLAAGTP
GMRHSLPNSRIMIHQPSAIQAEEIMKLKKQLYNIYAKHTKQSLQVIESAM
ERDRYMSPMEAQEFGILDKVLVHP
3D structure
PDB8w7e Design, synthesis and biological evaluations of novel small molecular hyper-activators of human caseinolytic peptidase P (hClpP)
ChainE
Resolution2.8 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9I3 E E82 I84 H116 Y118 W146 V148 E18 I20 H52 Y54 W82 V84
BS02 9I3 E L104 F105 S108 Y138 L40 F41 S44 Y74
External links
PDB RCSB:8w7e, PDBe:8w7e, PDBj:8w7e
PDBsum8w7e
PubMed
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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