Structure of PDB 8v2z Chain E

Receptor sequence
>8v2zE (length=372) Species: 9606 (Homo sapiens) [Search protein sequence]
ETTALVCDNGSGLCKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSY
VGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHSFYNELRVAPEEHPT
LLTEAPLNPKANREKMTQIMFETFNVPAMYVAIQAVLSLYASGRTTGIVL
DSGDGVTHNVPIYEGYALPHAIMRLDLAGRDLTDYLMKILTERGYSFVTT
AEREIVRDIKEKLCYVALDFENEMATAASSSSLEKSYELPDGQVITIGNE
RFCCPETLFQPSFIGMESAGIHETTYNSIMKCDIDIRKDLYANNVLSGGT
TMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQ
QMWISKPEYDEAGPSIVHRKCF
3D structure
PDB8v2z Smooth Muscle Gamma Actin (ACTG2) Filament Mutant R257C
ChainE
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP E G13 S14 G15 L16 K18 G156 D157 K213 E214 G302 M305 Y306 K336 G10 S11 G12 L13 K15 G153 D154 K210 E211 G299 M302 Y303 K333
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
Biological Process
GO:0010628 positive regulation of gene expression
GO:0090131 mesenchyme migration
Cellular Component
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0030027 lamellipodium
GO:0030175 filopodium
GO:0032982 myosin filament
GO:0044297 cell body
GO:0070062 extracellular exosome
GO:0071944 cell periphery
GO:0072562 blood microparticle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8v2z, PDBe:8v2z, PDBj:8v2z
PDBsum8v2z
PubMed
UniProtP63267|ACTH_HUMAN Actin, gamma-enteric smooth muscle (Gene Name=ACTG2)

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