Structure of PDB 8trl Chain E

Receptor sequence
>8trlE (length=179) Species: 9606 (Homo sapiens) [Search protein sequence]
DTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAVT
ELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVTV
YPANLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQTLV
MLETVPRSGEVYTCQVEHPSLTSPLTVEW
3D structure
PDB8trl T cell recognition of citrullinated alpha-enolase peptide presented by HLA-DR4
ChainE
Resolution2.4 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E H13 F26 Y30 D57 Y60 W61 Q70 K71 Y78 H81 N82 V85 H12 F25 Y29 D56 Y59 W60 Q69 K70 Y77 H80 N81 V84
External links
PDB RCSB:8trl, PDBe:8trl, PDBj:8trl
PDBsum8trl
PubMed39043656
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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