Structure of PDB 8tj6 Chain E

Receptor sequence
>8tj6E (length=317) Species: 380949 (Influenza A virus (A/Beijing/353/1989(H3N2))) [Search protein sequence]
PGATLCLGHHAVPNGTLVKTITNDQIEVTNATELVQSSSTGRICDSPHRI
LDGKNCTLIDALLGDPHCDGFQNKEWDLFVERSKAYSNCYPYDVPDYASL
RSLVASSGTLEFINEDFNWTGVAQSGESYACKRGSVKSFFSRLNWLHESE
YKYPALNVTMPNNGKFDKLYIWGVHHPSTDREQTNLYVRASGRVTVSTKR
SQQTVIPNIGSRPWVRGLSSRISIYWTIVKPGDILLINSTGNLIAPRGYF
KIRTGKSSIMRSDAPIGTCSSECITPNGSIPNDKPFQNVNRITYGACPRY
VKQNTLKLATGMRNVPE
3D structure
PDB8tj6 Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site.
ChainE
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SIA E Y98 S136 Y137 W153 H183 E190 L194 L226 S228 Y90 S128 Y129 W145 H175 E182 L186 L218 S220
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8tj6, PDBe:8tj6, PDBj:8tj6
PDBsum8tj6
PubMed38307019
UniProtO11283|HEMA_I89A2 Hemagglutinin (Gene Name=HA)

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