Structure of PDB 8th5 Chain E

Receptor sequence
>8th5E (length=131) Species: 9606 (Homo sapiens) [Search protein sequence]
EKPSPLLVGREFVRQYYTLLNQAPDLHRFYGKNSSYVHGGLDKPADAVYG
QKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQALRR
FMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
3D structure
PDB8th5 Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication.
ChainE
Resolution2.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E E14 R17 E11 R14
BS02 peptide E E14 F15 Q18 R32 F33 N122 K123 F124 Y125 E11 F12 Q15 R28 F29 N115 K116 F117 Y118
External links
PDB RCSB:8th5, PDBe:8th5, PDBj:8th5
PDBsum8th5
PubMed38492217
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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