Structure of PDB 8swp Chain E

Receptor sequence
>8swpE (length=281) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]
EQRALIKSAHRYISEKLEDHFSSEFLPKALVICGSGLSGISTKIADEPKP
LILSYSTIPGFKVSTVPGHSGELIFGYMNGAPVVLMNGRLHSYEGHSLAE
TVHPIRALHLLGSINVLIVTNAAGGINASFKAGDLMCVYDHINFPGLCGF
HDAYDLELRKLLFSKKKELNIERKIHEGTYSYVHGPTFESRAESRFLRLA
GTDAVGMSTVPEVVTARHCGWRVLALSLITNECVVDPPASAHDENPVPIQ
EGKATHEEVLENSAKASKDVQELIFSVVAEI
3D structure
PDB8swp Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
ChainE
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.2.1: purine-nucleoside phosphorylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HPA E A130 G131 F213 E214 M232 N256 A123 G124 F188 E189 M207 N231
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004731 purine-nucleoside phosphorylase activity
GO:0016757 glycosyltransferase activity
GO:0016763 pentosyltransferase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009116 nucleoside metabolic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8swp, PDBe:8swp, PDBj:8swp
PDBsum8swp
PubMed37812583
UniProtQ6CSZ6

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