Structure of PDB 8sos Chain E

Receptor sequence
>8sosE (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
MQRLFPLRCLQISSFANSSWTRTDGLAWLGELQTHSWSNDSDTVRSLKPW
SQGTFSDQQWETLQHIFRVYRSSFTRDVKEFAKMLRLSYPLELQVSAGCE
VHPGNASNNFFHVAFQGKDILSFQGTSWEPTQEAPLWVNLAIQVLNQDKW
TRETVQWLLNGTCPQFVSGLLESGKSELKKQVKPKAWLSRGPSPLLVCHV
SGFYPKPVWVKWRGEQEQQGTQPGDILPNADETWYLRATLVVAGEAAGLS
CRVKHSSLEGQDIVLYWG
3D structure
PDB8sos Enhanced CD1d phosphatidylserine presentation using a single-domain antibody promotes immunomodulatory CD1d-TIM-3 interactions.
ChainE
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FO4 E C12 L13 A30 F70 Y73 S76 R79 D80 F84 L90 W131 D151 T157 F169 C9 L10 A27 F67 Y70 S73 R76 D77 F81 L87 W128 D148 T154 F166
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:8sos, PDBe:8sos, PDBj:8sos
PDBsum8sos
PubMed38040419
UniProtP05412|JUN_HUMAN Transcription factor Jun (Gene Name=JUN);
P15813|CD1D_HUMAN Antigen-presenting glycoprotein CD1d (Gene Name=CD1D)

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