Structure of PDB 8s8j Chain E

Receptor sequence

>8s8jE (length=260) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

ARGPKKHLKRLAAPHHWMLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNR
LKYALNGREVKAILMQRHVKVDGKVRTDTTFPAGFMDVITLEATNENFRL
VYDVKGRFAVHRITDEEASYKLAKVKKVQLGKKGIPYVVTHDGRTIRYPD
PNIKVNDTVKVDLATGTITDFIKFDTGKLVYVTGGRNLGRVGTIVHRERH
EGGFDLVHIKDSLENTFVTRLNNVFVIGEPGRPWISLPKGKGIKLTISEE
RDRRRAQHGL

3D structure

PDB

8s8j Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

4.7 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	R3 G4 K6 K7 H8 K10 L12 H16 M19 D21 K22 L23 Y27 P29 A33 G34 H36 K37 L38 R49 N57 R59 K62 R77 K106 R108 Q130 L131 G132 K133 K134 G135 T146 R148 K155 T177 R187 H201 E202 I248 R255 L261	R2 G3 K5 K6 H7 K9 L11 H15 M18 D20 K21 L22 Y26 P28 A32 G33 H35 K36 L37 R48 N56 R58 K61 R76 K105 R107 Q129 L130 G131 K132 K133 G134 T145 R147 K154 T176 R186 H200 E201 I247 R254 L260

External links

PDB	RCSB:8s8j, PDBe:8s8j, PDBj:8s8j
PDBsum	8s8j
PubMed	39193907
UniProt	Q6CWJ2

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