Structure of PDB 8s8h Chain E

Receptor sequence

>8s8hE (length=260) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

ARGPKKHLKRLAAPHHWMLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNR
LKYALNGREVKAILMQRHVKVDGKVRTDTTFPAGFMDVITLEATNENFRL
VYDVKGRFAVHRITDEEASYKLAKVKKVQLGKKGIPYVVTHDGRTIRYPD
PNIKVNDTVKVDLATGTITDFIKFDTGKLVYVTGGRNLGRVGTIVHRERH
EGGFDLVHIKDSLENTFVTRLNNVFVIGEPGRPWISLPKGKGIKLTISEE
RDRRRAQHGL

3D structure

PDB

8s8h Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

4.0 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	R3 P5 K6 K7 H8 K10 R11 L12 H16 M19 D21 K22 Y27 P29 R30 A33 G34 H36 K37 L38 R49 N57 G58 R59 K62 M66 R77 T81 R108 L131 K133 K134 V140 T146 R148 K155 R187 H201 E202 F205 R255 L261	R2 P4 K5 K6 H7 K9 R10 L11 H15 M18 D20 K21 Y26 P28 R29 A32 G33 H35 K36 L37 R48 N56 G57 R58 K61 M65 R76 T80 R107 L130 K132 K133 V139 T145 R147 K154 R186 H200 E201 F204 R254 L260

External links

PDB	RCSB:8s8h, PDBe:8s8h, PDBj:8s8h
PDBsum	8s8h
PubMed	39193907
UniProt	Q6CWJ2

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