Structure of PDB 8rw1 Chain E

Receptor sequence

>8rw1E (length=260) Species: 284590 (Kluyveromyces lactis NRRL Y-1140) [Search protein sequence]

ARGPKKHLKRLAAPHHWMLDKLSGCYAPRPSAGPHKLRESLPLIVFLRNR
LKYALNGREVKAILMQRHVKVDGKVRTDTTFPAGFMDVITLEATNENFRL
VYDVKGRFAVHRITDEEASYKLAKVKKVQLGKKGIPYVVTHDGRTIRYPD
PNIKVNDTVKVDLATGTITDFIKFDTGKLVYVTGGRNLGRVGTIVHRERH
EGGFDLVHIKDSLENTFVTRLNNVFVIGEPGRPWISLPKGKGIKLTISEE
RDRRRAQHGL

3D structure

PDB

8rw1 Structural basis of AUC codon discrimination during translation initiation in yeast.

Chain

Resolution

3.35 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	rna	E	A2 R3 G4 P5 K6 K7 H8 K10 R11 L12 H16 M19 D21 K22 L23 Y27 P29 R30 A33 G34 K37 L38 R49 N57 G58 R59 M66 K75 R77 T81 K106 R108 Q130 L131 K133 K134 G135 V140 T146 R148 K155 G186 R187 H201 E202 F205 V219 R221 R255	A1 R2 G3 P4 K5 K6 H7 K9 R10 L11 H15 M18 D20 K21 L22 Y26 P28 R29 A32 G33 K36 L37 R48 N56 G57 R58 M65 K74 R76 T80 K105 R107 Q129 L130 K132 K133 G134 V139 T145 R147 K154 G185 R186 H200 E201 F204 V218 R220 R254

External links

PDB	RCSB:8rw1, PDBe:8rw1, PDBj:8rw1
PDBsum	8rw1
PubMed	39193907
UniProt	Q6CWJ2

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