Structure of PDB 8rh6 Chain E

Receptor sequence
>8rh6E (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEDGSHTIQIMYG
CDVGPDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HAAEQQRAYLEGRCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWE
3D structure
PDB8rh6 The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific.
ChainE
Resolution3.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Y7 Y9 E63 A69 Q70 T73 D74 D77 I97 Y99 I142 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167 Y7 Y9 E63 A69 Q70 T73 D74 D77 I97 Y99 I142 T143 K146 W147 A152 Q155 Q156 Y159 R163 W167
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:8rh6, PDBe:8rh6, PDBj:8rh6
PDBsum8rh6
PubMed38742159
UniProtQ5S3G3

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