Structure of PDB 8r04 Chain E

Receptor sequence
>8r04E (length=179) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
VPIVYDIYSRLLQDRIVLLGSPIDDHVANLIVAQLLFLESQDPDKDIYLY
INSPGGSVTAGLAIYDTMQYIKPDVVTICMGQAASMGAILLAAGAPGKRY
ALPHSRIMIHQPLGGIQGQATDIIIHAEEIKRIKEMLIDILAKHTGQPKD
KIANDIERDYFMSPYEAKDYGLIDKVIEK
3D structure
PDB8r04 Structure of Staphylococcus aureus ClpP Bound to the Covalent Active Site Inhibitor Cystargolide A
ChainE
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VSZ E G76 V78 S105 M106 H130 P132 L133 I153 G56 V58 S85 M86 H110 P112 L113 I133
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
GO:0051117 ATPase binding
Biological Process
GO:0006508 proteolysis
GO:0006515 protein quality control for misfolded or incompletely synthesized proteins
Cellular Component
GO:0005737 cytoplasm
GO:0009368 endopeptidase Clp complex

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Cellular Component
External links
PDB RCSB:8r04, PDBe:8r04, PDBj:8r04
PDBsum8r04
PubMed38029352
UniProtO67357|CLPP_AQUAE ATP-dependent Clp protease proteolytic subunit (Gene Name=clpP)

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