Structure of PDB 8q9r Chain E

Receptor sequence
>8q9rE (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
GRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHS
NKLFQYASTDMDKVLLKYTEYNEPHESRTNADIIETLRKKG
3D structure
PDB8q9r Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
ChainE
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E L67 Y69 T70 Y72 L66 Y68 T69 Y71
BS02 dna E G2 R3 K31 G1 R2 K30
BS03 dna E G2 R3 I6 K23 R24 K30 G1 R2 I5 K22 R23 K29
Gene Ontology
Molecular Function
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0046983 protein dimerization activity
Biological Process
GO:0045944 positive regulation of transcription by RNA polymerase II

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Molecular Function
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Biological Process
External links
PDB RCSB:8q9r, PDBe:8q9r, PDBj:8q9r
PDBsum8q9r
PubMed38492719
UniProtQ05BX2

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