Structure of PDB 8q0q Chain E

Receptor sequence
>8q0qE (length=214) Species: 9913 (Bos taurus) [Search protein sequence]
GALFVHRDTPENNPETPFDFTPENYKRIEAIVKNYPEGHKAAAVLPVLDL
AQRQNGWLPISAMNKVAEILQVPPMRVYEVATFYTMYNRKPVGKYHIQVC
TTTPCMLRNSDSILEAIQKKLGIKVGETTPDKLFTLIEVECLGACVNAPM
VQINDNYYEDLTPKDIEEIIDELKAGKIPKPGPRSGRFSCEPAGGLTSLT
EPPKGPGFGVQAGL
3D structure
PDB8q0q Molecular mechanism of the ischemia-induced regulatory switch in mammalian complex I
ChainE
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES E C103 P107 C108 C144 L145 G146 A147 C148 C100 P104 C105 C141 L142 G143 A144 C145
Gene Ontology
Molecular Function
GO:0003954 NADH dehydrogenase activity
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0045271 respiratory chain complex I

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8q0q, PDBe:8q0q, PDBj:8q0q
PDBsum8q0q
PubMed38870289
UniProtP04394|NDUV2_BOVIN NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (Gene Name=NDUFV2)

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