Structure of PDB 8pc6 Chain E

Receptor sequence
>8pc6E (length=97) Species: 8355 (Xenopus laevis) [Search protein sequence]
PHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSS
AVMALQEASEAYLVALFEDTNLAAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB8pc6 Multivalency of nucleosome recognition by LEDGF.
ChainE
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E Y41 V46 R63 L65 R69 Y4 V9 R26 L28 R32
BS02 dna E R40 Y41 R42 T45 R72 R83 F84 V117 T118 M120 R3 Y4 R5 T8 R35 R46 F47 V80 T81 M83
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:8pc6, PDBe:8pc6, PDBj:8pc6
PDBsum8pc6
PubMed37615563
UniProtP84233|H32_XENLA Histone H3.2

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