Structure of PDB 8osl Chain E

Receptor sequence
>8oslE (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAV
MALQEACEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRI
3D structure
PDB8osl Cooperation between bHLH transcription factors and histones for DNA access.
ChainE
Resolution4.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna E R40 Y41 P43 G44 V46 A47 R53 R63 K64 L65 R1 Y2 P4 G5 V7 A8 R14 R24 K25 L26
BS02 dna E R83 F84 Q85 R116 V117 T118 R44 F45 Q46 R77 V78 T79
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0045296 cadherin binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0010467 gene expression
GO:0032200 telomere organization
GO:0040029 epigenetic regulation of gene expression
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:8osl, PDBe:8osl, PDBj:8osl
PDBsum8osl
PubMed37407816
UniProtP68431|H31_HUMAN Histone H3.1 (Gene Name=H3C1)

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