Structure of PDB 8olt Chain E

Receptor sequence
>8oltE (length=214) Species: 10090 (Mus musculus) [Search protein sequence]
GALFVHRDTPENNPDTPFDFTPENYKRIEAIVKNYPEGHQAAAVLPVLDL
AQRQNGWLPISAMNKVAEVLQVPPMRVYEVATFYTMYNRKPVGKYHIQVC
TTTPCMLRDSDSILETLQRKLGIKVGETTPDKLFTLIEVECLGACVNAPM
VQINDNYYEDLTPKDIEEIIDELKAGKVPKPGPRSGRFCCEPAGGLTSLT
EPPKGPGFGVQAGL
3D structure
PDB8olt Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I.
ChainE
Resolution2.84 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FES E C103 P107 C108 C144 A147 C148 C100 P104 C105 C141 A144 C145
Gene Ontology
Molecular Function
GO:0008137 NADH dehydrogenase (ubiquinone) activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006120 mitochondrial electron transport, NADH to ubiquinone
GO:0007399 nervous system development
GO:0009060 aerobic respiration
GO:0042776 proton motive force-driven mitochondrial ATP synthesis
GO:0048738 cardiac muscle tissue development
GO:1902600 proton transmembrane transport
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0043209 myelin sheath
GO:0045271 respiratory chain complex I

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:8olt, PDBe:8olt, PDBj:8olt
PDBsum8olt
PubMed37531432
UniProtQ9D6J6|NDUV2_MOUSE NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (Gene Name=Ndufv2)

[Back to BioLiP]