Structure of PDB 8kd2 Chain E

Receptor sequence
>8kd2E (length=290) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KKRPKRLSSQNVNYDLKRRKIITSEGIERSFKNEENEDFCSACNQSGSFL
CCDTCPKSFHFLCLDPPIDPNNLPKGDWHCNECKFKIFKKIESNFIKQNN
NVKIFAKLLFNIDSHNPKQFQLPNYIKETFPAVKTGSRGQYSDENDTKLD
SYNPDTHIDSNSGKFLICYKCNQTRLGSWSHPENSRLIMTCDYCQTPWHL
DCVPRASFKNLGSKWKCPLHSPTKVYKNYKVWKKQRLINKKNQLYYEPLQ
KIGYQNNGNIQIIPDFKITQIDENSIKYDFFDKIYKSKMV
3D structure
PDB8kd2 Structural basis of nucleosome deacetylation and DNA linker tightening by Rpd3S histone deacetylase complex.
ChainE
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E Q510 K538 Y556 Q250 K267 Y285
BS02 peptide E P524 Y549 P264 Y278
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006368 transcription elongation by RNA polymerase II
GO:0030174 regulation of DNA-templated DNA replication initiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0060195 negative regulation of antisense RNA transcription
Cellular Component
GO:0000118 histone deacetylase complex
GO:0005634 nucleus
GO:0032221 Rpd3S complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8kd2, PDBe:8kd2, PDBj:8kd2
PDBsum8kd2
PubMed37666978
UniProtQ04779|RCO1_YEAST Transcriptional regulatory protein RCO1 (Gene Name=RCO1)

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