Structure of PDB 8ja7 Chain E

Receptor sequence

>8ja7E (length=443) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]

CGADSQGLVVSFYTPATDGATFTAIAQRCNQQFGGRFTIAQVSLPRSPNE
QRLQLARRLTGNDRTLDVMALDVVWTAEFAEAGWALPLSDDPAGLAENDA
VADTLPGPLATAGWNHKLYAAPVTTNTQLLWYRPDLVNSPPTDWNAMIAE
AARLHAAGEPSWIAVQANQGEGLVVWFNTLLVSAGGSVLSEDGRHVTLTD
TPAHRAATVSALQILKSVATTPGADPSITRTEEGSARLAFEQGKAALEVN
WPFVFASMLENAVKGGVPFLPLNRIPQLAGSINDIGTFTPSDEQFRIAYD
ASQQVFGFAPYPAVAPGQPAKVTIGGLNLAVAKTTRHRAEAFEAVRCLRD
QHNQRYVSLEGGLPAVRASLYSDPQFQAKYPMHAIIRQQLTDAAVRPATP
VYQALSIRLAAVLSPITEIDPESTADELAAQAQKAIDGMGLLP

3D structure

PDB

8ja7 Cryo-EM structure of Mycobacterium tuberculosis LpqY-SugABC in complex with trehalose

Chain

Resolution

3.02 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	GLC	E	P73 D97 W276 G350 G351 R421	P48 D72 W251 G325 G326 R396
BS02	GLC	E	T42 N151 F278	T17 N126 F253

External links

PDB	RCSB:8ja7, PDBe:8ja7, PDBj:8ja7
PDBsum	8ja7
PubMed	37603751
UniProt	P9WGU9\|LPQY_MYCTU Trehalose-binding lipoprotein LpqY (Gene Name=lpqY)

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