Structure of PDB 8iqk Chain E

Receptor sequence
>8iqkE (length=145) Species: 9606 (Homo sapiens) [Search protein sequence]
MSQSNRELVVDFLSYKLSQKGYSWSQFSDSEMAAVKQALREAGDEFELRY
RRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALC
VESVDKEMQVLVSRIAAWMATYLNDHLEPWIQENGGWDTFVELYG
3D structure
PDB8iqk Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival Bcl-2 family proteins.
ChainE
Resolution2.879 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide E F97 R100 Y101 F105 Q111 V126 L130 N136 G138 R139 Y195 F46 R49 Y50 F54 Q60 V75 L79 N85 G87 R88 Y144
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:8iqk, PDBe:8iqk, PDBj:8iqk
PDBsum8iqk
PubMed37560128
UniProtQ07817|B2CL1_HUMAN Bcl-2-like protein 1 (Gene Name=BCL2L1)

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