Structure of PDB 8igv Chain E

Receptor sequence
>8igvE (length=440) Species: 768486 (Enterococcus hirae ATCC 9790) [Search protein sequence]
IKEYRTIKEVVGPLMAVEKVSGVKYEELIEVRMQNGEIRRGQVLEVQEDK
AMVQIFEGTSGINLKNSSVRFLGHPLQLGVSEDMIGRVFDGLGRPKDNGP
EILPEKYLDINGEVINPIARDYPDEFIQTGISAIDHLNTLVRGQKLPVFG
PPGAGKSALAAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQT
GAIDRSVMFMNLANDPAIERIATPRMALTAAEYLAYEKGMHVLVIMEDMT
NYAEALREISAARREVPGRRGYPGYLYTNLATLFERAGRIRGLKGSVTQI
PILTMPEDDKTHPIPDLTGYITEGQIILTRELYKSGISPPIDVLPSLSRL
KDKGTGAGKTREDHAATMNQLFAAYAQGKQAKELSDIDKIYAKFAERFEN
EYVNQGFYTNRTITETLDLGWELLAMLPRTELKRIKDDLL
3D structure
PDB8igv Design of allosteric sites into rotary motor V 1 -ATPase by restoring lost function of pseudo-active sites.
ChainE
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP E G154 A155 G156 K157 S158 G153 A154 G155 K156 S157
BS02 MG E S158 E190 S157 E189
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
Biological Process
GO:0006814 sodium ion transport
GO:0042777 proton motive force-driven plasma membrane ATP synthesis
GO:0046034 ATP metabolic process
GO:1902600 proton transmembrane transport

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:8igv, PDBe:8igv, PDBj:8igv
PDBsum8igv
PubMed37414880
UniProtQ08637|NTPB_ENTHA V-type sodium ATPase subunit B (Gene Name=ntpB)

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