Structure of PDB 8i0i Chain E

Receptor sequence
>8i0iE (length=556) Species: 7227 (Drosophila melanogaster) [Search protein sequence]
MKYILVTGGVISGVGKGVIASSFGTLLKSCGLDVTSIKIDPYINIDAGTF
SPYEHGEVYVLDDGAEVDLDLGNYERFLDVTLHRDNNITTGKIYKLVIEK
ERTGEYLGKTVQVVPHITDAIQEWVERVAQTPVQGSSKPQVCIVELGGTI
GDIEGMPFVEAFRQFQFRVKRENFCLAHVSLVPLPKATGEPKTKPTQSSV
RELRGCGLSPDLIVCRSEKPIGLEVKEKISNFCHVGPDQVICIHDLNSIY
HVPLLMEQNGVIEYLNERLQLNIDMSKRTKCLQQWRDLARRTETVRREVC
IAVVGKYTKFTDSYASVVKALQHAALAVNRKLELVFIESCLLEEETLHSE
PSKYHKEWQKLCDSHGILVPGGFGSRGMEGKIRACQWARENQKPLLGICL
GLQAAVIEFARNKLGLKDANTTEIDPNTANALVIDMPEHHTGQLGGTMRL
GKRITVFSDGPSVIRQLYGNPKSVQERHRHRYEVNPKYVHLLEEQGMRFV
GTDVDKTRMEIIELSGHPYFVATQYHPEYLSRPLKPSPPFLGLILASVDR
LNQYIQ
3D structure
PDB8i0i Structural basis of bifunctional CTP/dCTP synthase
ChainE
Resolution3.5 Å
3D
structure
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Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 DUT E K192 T193 Q197 K228 K192 T193 Q197 K228
BS02 DTP E G13 G15 K16 G17 V18 K38 D70 R216 I249 V252 G13 G15 K16 G17 V18 K38 D70 R216 I249 V252
BS03 DUT E S12 K38 D40 Y42 G147 G148 E154 S12 K38 D40 Y42 G147 G148 E154
External links
PDB RCSB:8i0i, PDBe:8i0i, PDBj:8i0i
PDBsum8i0i
PubMed
UniProtQ9VUL1|PYRG_DROME CTP synthase (Gene Name=Ctps)

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