Structure of PDB 8i09 Chain E

Receptor sequence
>8i09E (length=245) Species: 90371 (Salmonella enterica subsp. enterica serovar Typhimurium) [Search protein sequence]
PCEELEIVWKNIKAEARALADCEPMLASFYHATLLKHENLGSALSYMLAN
KLASPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTP
LLYLKGFHALQAYRIGHWLWNKGRRALAIFLQNQVSVSFQVDIHPAAKIG
RGIMLDHATGIVVGETAVIEDDVSILQSVTLGGTGKTSGDRHPKIREGVM
IGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVPARIVGK
3D structure
PDB8i09 Alkyl gallates inhibit serine O -acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics.
ChainE
Resolution1.8 Å
3D
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Enzymatic activity
Enzyme Commision number 2.3.1.30: serine O-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CYS E R192 H193 R191 H192
BS02 NF0 E M201 G203 K219 I220 G221 A237 M200 G202 K218 I219 G220 A236
BS03 CYS E D92 D157 H158 D91 D156 H157
BS04 NF0 E G184 T185 G186 L227 G183 T184 G185 L226
Gene Ontology
Molecular Function
GO:0009001 serine O-acetyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0006535 cysteine biosynthetic process from serine
GO:0008652 amino acid biosynthetic process
GO:0019344 cysteine biosynthetic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:8i09, PDBe:8i09, PDBj:8i09
PDBsum8i09
PubMed37965540
UniProtA0A0D6I3Y9

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